Saturday, February 25, 2012

What happens to the DNA in the blood of a person when they donate blood to a recipient?

There is so much about DNA that we don't yet know. When foreign DNA enters our bodies through a blood transfusion, does that DNA combine with our own and continue to replicate? Does it degrade? Or does it continue to circulate with our own blood. Can donor blood DNA be found and identified at a crime scene and incriminate an innocent donor?What happens to the DNA in the blood of a person when they donate blood to a recipient?
Just as an interesting aside to the other answers; if you have a bone marrow transplant, your (white) blood cells do not carry your DNA anymore but the DNA of the donor, and your immature red cells (before they lose their nuclei) are also the donor's DNA--soooo in this case, blood at a crime scene would be screwy.
There are no cells in healthy blood which are able to replicate. The red blood cells are produced in the bone marrow, have no DNA, and die after about 120 days. White blood cells have DNA, and live from hours to years, depending on the type. But ... cells don't exchange or merge DNA, except in for sperm and egg cells in sexual reproduction.



Once the cell dies, its material disassociates, and is mostly flushed away in the urine.What happens to the DNA in the blood of a person when they donate blood to a recipient?
Blood does not contain DNA, only components such as RBC's, platelets, plasma, etc. When a person donates blood, none of their DNA is transmitted into the recipient. What is transferred that makes a HUGE difference is the portion that determines the blood type (eg - A+, AB-, O-, etc).



If someone else were to receive another person's DNA, then the host's body would see the strand as a foreign object (like bacteria) and immediately seek to destroy it as quickly as possible. This autoimmunity defense is what keeps our bodies as a separate, non-interchangeable unit with the rest of the population. Now there are some cases where twins may have similar DNA strands to a very high percentage, but there will always be some degree of indifference.



Hope this helps.
red blood cells and platelets have no DNA because they have no nucleus. red blood cells loose their nuclei when they leave the bone marrow and platelets are just cell fragments. white blood cells do have dna because they still have nuclei. this dna keeps the wbc functioning as a wbc. it has no affect on the donee. it doesnt degrade because it is needed to keep the cells going. i suppose transfused dna might show up in a person with a fresh transfusion. the dna doesnt mingle with the donee's dna. they are both contained in their own nuclei. donor dna does not continue to replicate. white blood cells are produced in the bone marrow. they do not go through mitosis.What happens to the DNA in the blood of a person when they donate blood to a recipient?
Red blood cells do not contain DNA, because they do not contain a nucleus.
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