Wednesday, February 29, 2012

What is the relationship between DNA and chromatin?

A. Chromatin means the collection of proteins encoded by DNA.

B. A chromatin is a DNA molecule that is separated during mitosis.

C. A chromatin is a unit of DNA whose sequence encode a protein.

D. Chromatin is the combination of DNA and associated proteins.

E. The chromatin is the protein structure that separates DNA chromosomes.What is the relationship between DNA and chromatin?
The answer is (D); Chromatin is the combination of DNA and associated proteins.



The "associated proteins" in this case are histones, which form octomers around which DNA wraps. The octomers themselves are organized into a spiral shape, creating a 30-nm chromatin fiber. These fibers themselves are further compacted around a "scaffold" of non-histone proteins.



The result is that a DNA molecule that may be almost a meter long is compacted into a chromosome that is only around 8 渭m in length.



Chromatin (with an N) should not be confused with chromatids (with a D), which would be answer (B) above. (Chromatids are also separated during the second meiotic division.)What is the relationship between DNA and chromatin?
D
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