these cells begin with the same DNA
and both stem from hematopoietic stem cells through differentiation
Haematopoietic stem cells (HSCs) reside in the medulla of the bone (bone marrow) and have the unique ability to give rise to all of the different mature blood cell types. HSCs are self renewing: when they proliferate, at least some of their daughter cells remain as HSCs, so the pool of stem cells does not become depleted. The other daughters of HSCs (myeloid and lymphoid progenitor cells), however can each commit to any of alternative differentiation pathways that lead to the production of one or more specific types of blood cells, but cannot self-renew. This is one of the vital processes in the body.
a normal person's system will produce 100 billion blood cells per day
but once they become specialized (differentiation, same thing) they become
All blood cells are divided into three lineages.
Erythroid cells are the oxygen carrying red blood cells. Both reticulocytes and erythrocytes are functional and are released into the blood. In fact, a reticulocyte count estimates the rate of erythropoiesis.
Lymphocytes are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid lineage is primarily composed of T-cells and B-cells (types of white blood cells). This is lymphopoiesis.
Myelocytes, which include granulocytes, megakaryocytes and macrophages and are derived from common myeloid progenitors, are involved in such diverse roles as innate immunity, adaptive immunity, and blood clotting. This is myelopoiesis.
Granulopoiesis (or granulocytopoiesis) is haematopoiesis of granulocytes.
Megakaryocytopoiesis is haematopoiesis of megakaryocytes.
this is not different DNA
it is done through cell signaling that's asking for different gene expression
like if i got a phone call saying "hey we need some more _______________ and _____________"
they think that what's going on is determined by the location of the differentiation
eg. the thymus provides an ideal environment for thymocytes to differentiate into a variety of different functional T cells. For the stem cells and other undifferentiated blood cells in the bone marrow, the determination is generally explained by the determinism theory of haematopoiesis, saying that colony stimulating factors and other factors of the haematopoietic microenvironment determine the cells to follow a certain path of cell differentiation. This is the classical way of describing haematopoiesis. In fact, however, it is not really true. The ability of the bone marrow to regulate the quantity of different cell types to be produced is more accurately explained by a stochastic theory: Undifferentiated blood cells are determined to specific cell types by randomness. The haematopoietic microenvironment prevails upon some of the cells to survive and some, on the other hand, to perform apoptosis and die. By regulating this balance between different cell types, the bone marrow can alter the quantity of different cells to ultimately be produced.What is the difference between the DNA in a red blood cell and a white blood cell?
New red blood cells are created by cell division of special stem cells but the red blood cells lose their DNA because they are not required to divide once in the blood stream.What is the difference between the DNA in a red blood cell and a white blood cell?
Mature red blood cells do not contain DNA! Part of their maturation is expelling the nucleus (and DNA within) to make more room for hemoglobin. White blood cells have nuclei and DNA within. In some of them (B lymphocytes) there are some rearrangements of DNA during synthesis of immunoglobulines (each cell line shall secrete only certain types of protein chains for immunoglobulines and shall keep the genes for only that type of Ig). Regarding proteins, there are manydifferencess, since red blood cells contain hemoglobin mainly, and white blood cells produce a bunch of proteins (Ig, cytokines, etc.).
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