Saturday, March 10, 2012

What is the sequence of bases on the complimentary DNA strand?

One strand of DNA molecule has the base sequence GATTCGTA

I don't get it.What is the sequence of bases on the complimentary DNA strand?
A goes with T and G goes with C due to complimentary base pairing.Just match them up.What is the sequence of bases on the complimentary DNA strand?
The bases that are "complimentary" are CTAAGCAT.

DNA is double stranded and G's pair with C's, and A's pair with T's



But DNA is directional too, with one strand running in one direction, and the other strand running in the opposite direction.



So the actual sequence that would pair with GATTCGTA, is TACGAATC, which is the reverse compliment. So be mindful of that if you are ever doing something like designing primers for PCR.

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